Search Ontology:
GO: Biological Process
pyroptotic inflammatory response
- Term ID
- GO:0070269
- Synonyms
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- pyroptosis
- Definition
- A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. (3)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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- has subtype
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- negatively regulated by
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- positively regulated by
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Phenotype
Phenotype caused by Genes