mRNA destabilization

Term ID

GO:0061157

Synonyms

Definition

Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: negative regulation of gene expression positive regulation of mRNA catabolic process regulation of mRNA stability RNA destabilization

negative regulation of gene expression positive regulation of mRNA catabolic process regulation of mRNA stability RNA destabilization Show first 5 Terms
has subtype: 3'-UTR-mediated mRNA destabilization miRNA-mediated gene silencing by mRNA destabilization nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay piRNA-mediated gene silencing by mRNA destabilization polyadenylation-dependent mRNA catabolic process ... Show All 8 Terms

3'-UTR-mediated mRNA destabilization miRNA-mediated gene silencing by mRNA destabilization nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay piRNA-mediated gene silencing by mRNA destabilization polyadenylation-dependent mRNA catabolic process polyuridylation-dependent mRNA catabolic process siRNA-mediated gene silencing by mRNA destabilization transposable element silencing by mRNA destabilization Show first 5 Terms
inverse has_part: global gene silencing by mRNA cleavage

global gene silencing by mRNA cleavage Show first 5 Terms

Phenotype

Phenotype caused by Genes