Wnt signaling pathway, planar cell polarity pathway

Term ID

GO:0060071

Synonyms

• PCP pathway
• planar cell polarity pathway
• Wnt receptor signaling pathway, planar cell polarity pathway
• Wnt receptor signalling pathway, planar cell polarity pathway
• Wnt-activated signaling pathway, planar cell polarity pathway
• Wnt-JNK signaling pathway
• Wnt-PCP signaling pathway

Definition

A type of non-canonical Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the activation small G proteins such as Rho, Rac, and Cdc42 which, in turn activate effectors, including C-Jun N-terminal kinase (JNK) and Rho kinase (Rok). The signaling ends with change in the transcription of target genes and/or reorganisation of the cytoskeleton. (4)

References

• Reactome:R-HSA-4086400

Ontology

GO: Biological Process    QuickGO    AmiGO