G-quadruplex DNA binding

Term ID

GO:0051880

Synonyms

• G quadruplex DNA binding
• G quartet binding
• G quartet DNA binding
• G-DNA binding
• G-quartet binding
• G-quartet DNA binding
• quadruplex DNA binding
• tetraplex DNA binding

Definition

Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. (2)

References

Ontology

GO: Molecular Function    QuickGO    AmiGO