dermatan sulfate proteoglycan biosynthetic process

Term ID

GO:0050651

Synonyms

• chondroitin sulfate B proteoglycan biosynthesis
• chondroitin sulfate B proteoglycan biosynthetic process
• dermatan sulfate proteoglycan anabolism
• dermatan sulfate proteoglycan biosynthesis
• dermatan sulfate proteoglycan formation
• dermatan sulfate proteoglycan synthesis
• dermatan sulphate proteoglycan biosynthesis
• dermatan sulphate proteoglycan biosynthetic process

Definition

The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycans, which consist of a core protein linked to a dermatan sulfate glycosaminoglycan. The dermatan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-D-hexuronic acid-beta-(1,3)-N-acetyl-D-galactosamine. Tthe former can be a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter can be O-sulfated. Dermatan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate). 17239763

References

• MetaCyc:PWY-6568

Ontology

GO: Biological Process    QuickGO    AmiGO