Search Ontology:
GO: Biological Process

isotype switching to IgG isotypes

Term ID
GO:0048291
Synonyms
  • class switching to IgG isotypes
  • isotype switch recombination to IgG isotypes
Definition
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. (4)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes
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