lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity

Term ID

GO:0047256

Synonyms

• beta1->3-N-acetylglucosaminyltransferase activity
• LA2 synthase activity
• lactosylceramide beta-acetylglucosaminyltransferase activity
• UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity
• uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity

Definition

Catalysis of the reaction: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H+ + UDP.

References

• EC:2.4.1.206
• MetaCyc:2.4.1.206-RXN
• RHEA:13905
• Reactome:R-HSA-9846501

Ontology

GO: Molecular Function    QuickGO    AmiGO