tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent

Term ID

GO:0047151

Synonyms

• 5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity
• 5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity
• folate-dependent ribothymidyl synthase activity
• methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity
• methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity
• tRNA (uracil(54)-C(5))-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent

Definition

Catalysis of the reaction: uridine54 in tRNA + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(P)H + H+ = 5-methyluridine54 in tRNA + (6S)-5,6,7,8-tetrahydrofolate + NAD(P)+. 2.1.1.74

References

• EC:2.1.1.74
• KEGG_REACTION:R03704
• MetaCyc:2.1.1.74-RXN
• RHEA:16873
• RHEA:62372

Ontology

GO: Molecular Function    QuickGO    AmiGO