1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Term ID

GO:0046934

Synonyms

• phosphatidylinositol 3-kinase activity, class I
• phosphatidylinositol 3-kinase activity, class II
• phosphatidylinositol 3-kinase, class I, catalyst activity
• phosphatidylinositol-4,5-bisphosphate 3-kinase activity
• type I phosphoinositide 3-kinase activity

Definition

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H+. 2.7.1.153

References

• EC:2.7.1.153
• KEGG_REACTION:R04545
• MetaCyc:2.7.1.153-RXN
• RHEA:21292
• Reactome:R-HSA-1226014
• Reactome:R-HSA-1250370
• Reactome:R-HSA-1250462
• Reactome:R-HSA-1306957
• Reactome:R-HSA-1306979
• Reactome:R-HSA-1676048
• Reactome:R-HSA-177939
• Reactome:R-HSA-1839091
• Reactome:R-HSA-1839107
• Reactome:R-HSA-186800
• Reactome:R-HSA-198266
• Reactome:R-HSA-201510
• Reactome:R-HSA-202365
• Reactome:R-HSA-2029271
• Reactome:R-HSA-2076220
• Reactome:R-HSA-2316434
• Reactome:R-HSA-2394007
• Reactome:R-HSA-2424480
• Reactome:R-HSA-2730870
• Reactome:R-HSA-389158
• Reactome:R-HSA-392300
• Reactome:R-HSA-437162
• Reactome:R-HSA-5218819
• Reactome:R-HSA-5637801
• Reactome:R-HSA-5654690
• Reactome:R-HSA-5654692
• Reactome:R-HSA-5654697
• Reactome:R-HSA-5654701
• Reactome:R-HSA-5654705
• Reactome:R-HSA-5654709
• Reactome:R-HSA-5654714
• Reactome:R-HSA-5654717
• Reactome:R-HSA-5655235
• Reactome:R-HSA-5655289
• Reactome:R-HSA-5655290
• Reactome:R-HSA-5655323
• Reactome:R-HSA-8852019
• Reactome:R-HSA-9021627
• Reactome:R-HSA-9603445
• Reactome:R-HSA-9664664
• Reactome:R-HSA-9664940
• Reactome:R-HSA-9665407
• Reactome:R-HSA-9672162
• Reactome:R-HSA-9672177
• Reactome:R-HSA-9712084

Ontology

GO: Molecular Function    QuickGO    AmiGO