Search Ontology:
GO: Biological Process

isotype switching

Term ID
GO:0045190
Synonyms
  • class switch recombination
  • class switching
  • isotype switch recombination
Definition
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. 0781735149
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
Phenotype
Phenotype caused by Genes
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