NADPH oxidase complex

Term ID

GO:0043020

Synonyms

• flavocytochrome b558
• respiratory-burst oxidase

Definition

A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires the cytosolic regulatory subunits at least NCF1/p47-phox, NCF2/p67-phox, NCF4/p40-phox and the small GTPase RAC1 or RAC2 for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO