Search Ontology:
GO: Cellular Component

MHC class I peptide loading complex

Term ID
GO:0042824
Synonyms
  • peptide-loading complex
  • PLC
Definition
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. 10631934
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
has parts
is a type of
Phenotype
Phenotype caused by Genes
Citations
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