GSI anchor biosynthetic process

Term ID

GO:0042082

Synonyms

• GPI/GSI anchor biosynthesis
• GPI/GSI anchor biosynthetic process
• GSI anchor anabolism
• GSI anchor biosynthesis
• GSI anchor formation
• GSI anchor synthesis

Definition

The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.

References

Ontology

GO: Biological Process    QuickGO    AmiGO