symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity

Term ID

GO:0039540

Synonyms

• inhibition by virus of host DDX58 activity
• inhibition by virus of host RIG-I
• inhibition by virus of host RIG-I signaling
• inhibition of host DDX58/RIG-I by virus
• suppression by virus of host DDX58 signaling pathway
• suppression by virus of host RIG-I activity
• suppression by virus of host RIG-I signaling pathway
• suppression by virus of host RIG-I signalling pathway
• suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity

Definition

A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. (2)

References

• VZ:856

Ontology

GO: Biological Process    QuickGO    AmiGO