ERBB4-EGFR signaling pathway

Term ID

GO:0038137

Synonyms

• ERBB1-ERBB4 signaling pathway
• ERBB4-EGFR signalling pathway
• HER1-HER4 signaling pathway

Definition

The series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. 16460914

References

Ontology

GO: Biological Process    QuickGO    AmiGO