Search Ontology:
GO: Biological Process

ERBB2 signaling pathway

Term ID
GO:0038128
Synonyms
  • ERBB2 signalling pathway
  • HER2 signaling pathway
  • NEU signaling
  • receptor tyrosine-protein kinase erbB-2 signaling pathway
Definition
The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. 16460914
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes