Search Ontology:
GO: Biological Process
ERBB2 signaling pathway
- Term ID
- GO:0038128
- Synonyms
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- ERBB2 signalling pathway
- HER2 signaling pathway
- NEU signaling
- receptor tyrosine-protein kinase erbB-2 signaling pathway
- Definition
- The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. 16460914
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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- has subtype
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Phenotype
Phenotype caused by Genes