peptide bond cleavage involved in epidermal growth factor receptor ligand maturation

Term ID

GO:0038005

Synonyms

• EGFR ligand maturation by peptide bond cleavage
• EGFR ligand processing
• epidermal growth factor receptor ligand processing
• peptide bond cleavage involved in EGFR ligand maturation

Definition

The hydrolysis of a peptide bond or bonds within a ligand for the epidermal growth factor receptor, as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. In Drosophila for example, in the Golgi apparatus of the signal producing cell, Spitz is cleaved within its transmembrane domain to release a functional soluble extracellular fragment.

References

Secondary ID:

Merged into

epidermal growth factor receptor ligand maturation

Ontology

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