TRAIL-activated apoptotic signaling pathway

Term ID

GO:0036462

Synonyms

TRAIL-activated extrinsic apoptotic signaling pathway
TRAIL-induced apoptotic signaling pathway
tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway

Definition

An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface. 21785459

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: TRAIL death-inducing signaling complex assembly TRAIL receptor activity

TRAIL death-inducing signaling complex assembly TRAIL receptor activity Show first 5 Terms
is a type of: extrinsic apoptotic signaling pathway via death domain receptors

extrinsic apoptotic signaling pathway via death domain receptors Show first 5 Terms
negatively regulated by: negative regulation of TRAIL-activated apoptotic signaling pathway

negative regulation of TRAIL-activated apoptotic signaling pathway Show first 5 Terms
positively regulated by: positive regulation of TRAIL-activated apoptotic signaling pathway

positive regulation of TRAIL-activated apoptotic signaling pathway Show first 5 Terms
regulated by: regulation of TRAIL-activated apoptotic signaling pathway

regulation of TRAIL-activated apoptotic signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations