Search Ontology:
GO: Biological Process

interstrand cross-link repair

Term ID
GO:0036297
Synonyms
  • ICL repair
Definition
Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. (2)
References
  • Reactome:R-HSA-6783310
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
has parts
is a type of
has subtype
Phenotype
Phenotype caused by Genes
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