site of double-strand break

Term ID

GO:0035861

Synonyms

• DNA damage foci
• DNA damage focus
• ionizing radiation-induced foci
• IRIF
• site of DSB

Definition

A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO