mitochondrial prohibitin complex

Term ID

GO:0035632

Synonyms

• mitochondrial inner membrane prohibitin complex

Definition

A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO