Notch receptor processing, ligand-independent

Term ID

GO:0035334

Synonyms

• Notch S1 cleavage

Definition

The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface. 12651094

References

Ontology

GO: Biological Process    QuickGO    AmiGO