Search Ontology:
GO: Cellular Component

ESC/E(Z) complex

Term ID
GO:0035098
Synonyms
  • Extra Sex Combs/Enhancer of Zeste complex
  • polycomb repressive complex 2
  • PRC2 complex
Definition
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. (6)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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