low-density lipoprotein particle remodeling

Term ID

GO:0034374

Synonyms

• LDL remodeling
• LDL remodelling
• low-density lipoprotein particle remodelling
• small dense LDL formation
• small dense low-density lipoprotein particle formation

Definition

The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.

References

• Reactome:R-HSA-8964041

Ontology

GO: Biological Process    QuickGO    AmiGO