TSC1-TSC2 complex

Term ID

GO:0033596

Synonyms

• tuberin-hamartin complex
• tuberous sclerosis complex

Definition

A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. (3)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO