tumor necrosis factor-mediated signaling pathway

Term ID

GO:0033209

Synonyms

adipocytokine signaling pathway
TNF-alpha-mediated signaling pathway
tumor necrosis factor alpha-mediated signaling pathway
tumor necrosis factor-mediated signalling pathway

Definition

The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

References

Reactome:R-HSA-5668541
Reactome:R-HSA-75893

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: cellular response to tumor necrosis factor

cellular response to tumor necrosis factor Show first 5 Terms
has parts: tumor necrosis factor receptor activity

tumor necrosis factor receptor activity Show first 5 Terms
is a type of: cytokine-mediated signaling pathway

cytokine-mediated signaling pathway Show first 5 Terms
negatively regulated by: negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of tumor necrosis factor-mediated signaling pathway Show first 5 Terms
positively regulated by: positive regulation of tumor necrosis factor-mediated signaling pathway

positive regulation of tumor necrosis factor-mediated signaling pathway Show first 5 Terms
regulated by: regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes