proton-transporting V-type ATPase complex

Term ID

GO:0033176

Synonyms

hydrogen-translocating V-type ATPase complex

Definition

A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. (2)

References

Ontology

GO: Cellular Component QuickGO AmiGO

Relationships

has parts: proton-transporting V-type ATPase, V0 domain proton-transporting V-type ATPase, V1 domain

proton-transporting V-type ATPase, V0 domain proton-transporting V-type ATPase, V1 domain Show first 5 Terms
is a type of: ATPase complex cation-transporting ATPase complex proton-transporting two-sector ATPase complex

ATPase complex cation-transporting ATPase complex proton-transporting two-sector ATPase complex Show first 5 Terms
has subtype: lysosomal proton-transporting V-type ATPase complex plasma membrane proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex

lysosomal proton-transporting V-type ATPase complex plasma membrane proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex Show first 5 Terms

Phenotype

Phenotype caused by Genes