plasminogen activation

Term ID

GO:0031639

Synonyms

• cleavage of plasminogen to plasmin

Definition

The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. 9548733

References

Ontology

GO: Biological Process    QuickGO    AmiGO