Search Ontology:
GO: Cellular Component
replication fork protection complex
- Term ID
- GO:0031298
- Synonyms
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- fork pausing complex
- Swi1-Swi3 complex
- TIMELESS-TIPIN complex
- Definition
- A heterotrimeric replication-pausing complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. Required for maximal fork speed both in vivo and in vitro. (3)
- References
- Ontology
- GO: Cellular Component QuickGO AmiGO
- is part of
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- is a type of
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Phenotype
Phenotype caused by Genes