Search Ontology:
GO: Cellular Component

beta-catenin destruction complex

Term ID
GO:0030877
Synonyms
  • 23S APC complex
  • APC-Axin-1-beta-catenin complex
  • Axin-APC-beta-catenin-GSK3B complex
  • BDC
  • beta-catenin degradation complex
Definition
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. 14600025
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.