Mre11 complex

Term ID

GO:0030870

Synonyms

• MRN complex
• MRX complex
• Rad50 complex
• RAD50-MRE11-NBN complex
• Rad50-Rad32-Nbs1 complex
• RMX complex

Definition

Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO