T cell differentiation

Term ID

GO:0030217

Synonyms

T cell development
T lymphocyte differentiation
T-cell differentiation
T-lymphocyte differentiation

Definition

The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: pro-T cell differentiation somatic diversification of T cell receptor genes T cell lineage commitment T cell selection

pro-T cell differentiation somatic diversification of T cell receptor genes T cell lineage commitment T cell selection Show first 5 Terms
is a type of: lymphocyte differentiation T cell activation

lymphocyte differentiation T cell activation Show first 5 Terms
has subtype: alpha-beta T cell differentiation cytotoxic T cell differentiation exhausted T cell differentiation extrathymic T cell differentiation gamma-delta T cell differentiation ... Show All 8 Terms

alpha-beta T cell differentiation cytotoxic T cell differentiation exhausted T cell differentiation extrathymic T cell differentiation gamma-delta T cell differentiation regulatory T cell differentiation T cell differentiation in thymus T cell differentiation involved in immune response Show first 5 Terms
inverse capable_of: pro-T cell

pro-T cell Show first 5 Terms
inverse has_completed: CD4-positive helper T cell CD4-positive, alpha-beta cytotoxic T cell CD8-positive, alpha-beta cytokine secreting effector T cell CD8-positive, alpha-beta cytotoxic T cell CD27-negative gamma-delta T cell ... Show All 9 Terms

CD4-positive helper T cell CD4-positive, alpha-beta cytotoxic T cell CD8-positive, alpha-beta cytokine secreting effector T cell CD8-positive, alpha-beta cytotoxic T cell CD27-negative gamma-delta T cell CD27-positive gamma-delta T cell effector T cell mature NK T cell mucosal invariant T cell Show first 5 Terms
negatively regulated by: negative regulation of T cell differentiation

negative regulation of T cell differentiation Show first 5 Terms
positively regulated by: positive regulation of T cell differentiation

positive regulation of T cell differentiation Show first 5 Terms
regulated by: regulation of T cell differentiation

regulation of T cell differentiation Show first 5 Terms

Phenotype

Phenotype caused by Genes