ammonia assimilation cycle

Term ID

GO:0019676

Synonyms

• glutamate metabolic process via glutamine and ammonia
• glutamate metabolism via glutamine and ammonia

Definition

The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.

References

• MetaCyc:AMMASSIM-PWY
• MetaCyc:PWY-3282
• MetaCyc:PWY-6963
• MetaCyc:PWY-6964

Ontology

GO: Biological Process    QuickGO    AmiGO