NAD-dependent histone deacetylase activity

Term ID

GO:0017136

Synonyms

SIR2

Definition

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone. 28450737

References

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: histone deacetylase activity NAD-dependent protein lysine deacetylase activity

histone deacetylase activity NAD-dependent protein lysine deacetylase activity Show first 5 Terms
has subtype: NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H3K14 deacetylase activity NAD-dependent histone H3K18 deacetylase activity NAD-dependent histone H3K56 deacetylase activity NAD-dependent histone H4K16 deacetylase activity

NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H3K14 deacetylase activity NAD-dependent histone H3K18 deacetylase activity NAD-dependent histone H3K56 deacetylase activity NAD-dependent histone H4K16 deacetylase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations