Search Ontology:
GO: Cellular Component

NuRD complex

Term ID
GO:0016581
Synonyms
  • Mi-2 complex
  • NRD complex
  • nucleosome remodeling and histone deacetylation complex
Definition
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. (3)
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
has subtype
Phenotype
Phenotype caused by Genes
Citations
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