dystrophin-associated glycoprotein complex

Term ID

GO:0016010

Synonyms

• DGC
• dystrophin glycoprotein complex

Definition

A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO