type I site-specific deoxyribonuclease activity

Term ID

GO:0009035

Synonyms

adenosine triphosphate-dependent deoxyribonuclease activity
ATP-dependent DNase activity
deoxyribonuclease (adenosine triphosphate-hydrolyzing)
deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)
type I restriction enzyme activity

Definition

Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. (2)

References

EC:3.1.21.3
MetaCyc:3.1.21.3-RXN

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: DNA translocase activity endodeoxyribonuclease activity, producing 5'-phosphomonoesters restriction endodeoxyribonuclease activity

DNA translocase activity endodeoxyribonuclease activity, producing 5'-phosphomonoesters restriction endodeoxyribonuclease activity Show first 5 Terms
negatively regulated by: negative regulation of type I site-specific deoxyribonuclease activity

negative regulation of type I site-specific deoxyribonuclease activity Show first 5 Terms
regulated by: regulation of type I site-specific deoxyribonuclease activity

regulation of type I site-specific deoxyribonuclease activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations