DNA-3-methyladenine glycosylase activity

Term ID

GO:0008725

Synonyms

• 3-methyladenine DNA glycosylase I
• alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
• deoxyribonucleate 3-methyladenine glycosidase I
• DNA glycosidase I activity
• DNA-3-methyladenine glycosidase I activity
• DNA-3-methyladenine glycosylase I activity

Definition

Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site. (3)

References

• EC:3.2.2.20
• EC:3.2.2.21
• MetaCyc:3.2.2.21-RXN
• MetaCyc:RXN0-5189

Ontology

GO: Molecular Function    QuickGO    AmiGO