intrinsic apoptotic signaling pathway in response to DNA damage

Term ID

GO:0008630

Synonyms

• DNA damage response, signal transduction resulting in induction of apoptosis

Definition

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.

References

Ontology

GO: Biological Process    QuickGO    AmiGO