CHRAC

Term ID

GO:0008623

Synonyms

• chromatin accessibility complex
• ISW2 complex

Definition

An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair. (4)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO