DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

Term ID

GO:0006978

Synonyms

Definition

A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage. 10967424

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction resulting in transcription

DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction resulting in transcription Show first 5 Terms
negatively regulated by: negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Show first 5 Terms
positively regulated by: positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Show first 5 Terms
regulated by: regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations