base-excision repair

Term ID

GO:0006284

Synonyms

Definition

In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. 0815316194

References

Reactome:R-HSA-73884
Reactome:R-HSA-73930
Wikipedia:Base_excision_repair

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: base-excision repair, AP site formation base-excision repair, gap-filling

base-excision repair, AP site formation base-excision repair, gap-filling Show first 5 Terms
is a type of: DNA repair

DNA repair Show first 5 Terms
has subtype: telomere maintenance via base-excision repair

telomere maintenance via base-excision repair Show first 5 Terms
negatively regulated by: negative regulation of base-excision repair

negative regulation of base-excision repair Show first 5 Terms
positively regulated by: positive regulation of base-excision repair

positive regulation of base-excision repair Show first 5 Terms
regulated by: regulation of base-excision repair

regulation of base-excision repair Show first 5 Terms

Phenotype

Phenotype caused by Genes