Search Ontology:
GO: Cellular Component

mitochondrial permeability transition pore complex

Term ID
GO:0005757
Synonyms
  • mitochondrial PT pore complex
  • MPTP complex
  • PTPC
Definition
A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). 10393078
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes
Citations
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