inward rectifier potassium channel activity

Term ID

GO:0005242

Synonyms

• Kir channel activity

Definition

Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. 14977398

References

• Reactome:R-HSA-1296045
• Reactome:R-HSA-1296046
• Reactome:R-HSA-1369017
• Reactome:R-HSA-5678261
• Reactome:R-HSA-5678418
• Reactome:R-HSA-9729870
• Reactome:R-HSA-9730521
• Reactome:R-HSA-9731072

Ontology

GO: Molecular Function    QuickGO    AmiGO