phosphoprotein phosphatase activity

Term ID

GO:0004721

Synonyms

phosphoprotein phosphohydrolase activity
protein phosphatase activity
protein phosphatase-1 activity
protein phosphatase-2A activity
protein phosphatase-2B activity
protein phosphatase-2C activity

Definition

Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity. 0198547684

References

Reactome:R-HSA-112383
Reactome:R-HSA-113503
Reactome:R-HSA-1363274
Reactome:R-HSA-1363276
Reactome:R-HSA-167072
Reactome:R-HSA-170153
Reactome:R-HSA-170158
Reactome:R-HSA-170161
Reactome:R-HSA-174110
Reactome:R-HSA-174124
Reactome:R-HSA-178178
Reactome:R-HSA-2529015
Reactome:R-HSA-69199
Reactome:R-HSA-9636684

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: catalytic activity, acting on a protein phosphatase activity

catalytic activity, acting on a protein phosphatase activity Show first 5 Terms
has subtype: [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity [acetyl-CoA carboxylase]-phosphatase activity [glycogen-synthase-D] phosphatase activity [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity [isocitrate dehydrogenase (NADP+)] phosphatase activity ... Show All 17 Terms

[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity [acetyl-CoA carboxylase]-phosphatase activity [glycogen-synthase-D] phosphatase activity [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity [isocitrate dehydrogenase (NADP+)] phosphatase activity [phosphorylase] phosphatase activity [pyruvate kinase]-phosphatase activity histone phosphatase activity MAP kinase phosphatase activity myosin-light-chain-phosphatase activity protein arginine phosphatase activity protein histidine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity transmembrane receptor protein phosphatase activity Show first 5 Terms
negatively regulated by: protein phosphatase inhibitor activity

protein phosphatase inhibitor activity Show first 5 Terms
positively regulated by: protein phosphatase activator activity

protein phosphatase activator activity Show first 5 Terms
regulated by: protein phosphatase regulator activity

protein phosphatase regulator activity Show first 5 Terms

Phenotype

Phenotype caused by Genes