Search Ontology:

GO: Molecular Function

nitric-oxide synthase activity

Term ID

GO:0004517

Synonyms

endothelium-derived relaxation factor-forming enzyme activity
endothelium-derived relaxing factor synthase activity
L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity
NADPH-diaphorase activity
nitric oxide synthase activity
nitric oxide synthetase activity
nitric-oxide synthetase activity
NO synthase activity

Definition

Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. 1.14.13.39

References

EC:1.14.13.39
MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN
RHEA:19897
Reactome:R-HSA-202127
Reactome:R-HSA-418436

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Show first 5 Terms
negatively regulated by: negative regulation of nitric-oxide synthase activity

negative regulation of nitric-oxide synthase activity Show first 5 Terms
positively regulated by: positive regulation of nitric-oxide synthase activity

positive regulation of nitric-oxide synthase activity Show first 5 Terms
regulated by: regulation of nitric-oxide synthase activity

regulation of nitric-oxide synthase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations