methyltransferase cap1 activity

Term ID

GO:0004483

Synonyms

• messenger ribonucleate nucleoside 2'-methyltransferase activity
• messenger RNA (nucleoside-2'-)-methyltransferase activity
• mRNA (adenosine-2'-O-)-methyltransferase activity
• mRNA (nucleoside-2'-O-)-methyltransferase activity
• S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity

Definition

Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the first transcribed nucleotide of mRNAs and snRNAs. 2.1.1.57

References

• EC:2.1.1.57
• MetaCyc:2.1.1.57-RXN
• Reactome:R-HSA-9684030
• Reactome:R-HSA-9684032
• Reactome:R-HSA-9684033
• Reactome:R-HSA-9694499
• Reactome:R-HSA-9694521
• Reactome:R-HSA-9694721
• Reactome:R-HSA-9834003

Ontology

GO: Molecular Function    QuickGO    AmiGO