serine-type endopeptidase activity

Term ID

GO:0004252

Synonyms

• blood coagulation factor activity
• serine elastase activity

Definition

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE

References

• EC:3.4.21.-
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Ontology

GO: Molecular Function    QuickGO    AmiGO