Search Ontology:
GO: Molecular Function

dihydrofolate reductase activity

Term ID
GO:0004146
Synonyms
  • 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity
  • 7,8-dihydrofolate reductase activity
  • DHFR
  • dihydrofolate reductase:thymidylate synthase activity
  • dihydrofolate reduction
  • dihydrofolic acid reductase activity
  • dihydrofolic reductase activity
  • folic acid reductase activity
  • folic reductase activity
  • NADPH-dihydrofolate reductase activity
  • pteridine reductase:dihydrofolate reductase activity
  • tetrahydrofolate dehydrogenase activity
  • thymidylate synthetase-dihydrofolate reductase activity
(all 13)
Definition
Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. 1.5.1.3
References
  • EC:1.5.1.3
  • MetaCyc:DIHYDROFOLATEREDUCT-RXN
  • RHEA:15009
  • Reactome:R-HSA-1497794
(all 4)
Ontology
GO: Molecular Function    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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