Search Ontology:
GO: Molecular Function
aconitate hydratase activity
- Term ID
- GO:0003994
- Synonyms
-
- aconitase activity
- cis-aconitase activity
- citrate hydro-lyase activity
- citrate(isocitrate) hydro-lyase (cis-aconitate-forming)
- citrate(isocitrate) hydro-lyase activity
- Definition
- Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. 4.2.1.3
- References
-
- EC:4.2.1.3
- MetaCyc:RXN-14047
- RHEA:10336
- Reactome:R-HSA-5690911
- Reactome:R-HSA-70971
- Ontology
- GO: Molecular Function QuickGO AmiGO
- is a type of
-
- negatively regulated by
-
- positively regulated by
-
Phenotype
Phenotype caused by Genes